Life expectancy of patients with chronic nonleukemic myeloproliferative disorders
نویسندگان
چکیده
منابع مشابه
Incidence of pulmonary hypertension in patients with chronic myeloproliferative disorders.
STUDY OBJECTIVE To assess the incidence of pulmonary hypertension (PH) in patients with chronic myeloproliferative disorders (CMPD). METHOD Twenty-seven patients with a diagnosis of CMPD were included in the study. Patients were excluded if they had a secondary cause of PH. Diagnosis of PH was established if right ventricular systolic pressure (RVSP) by transthoracic echocardiography (TTE) wa...
متن کاملChronic Myeloproliferative Disorders
JAK2, an acquired mutation of JAK2, is present in a majority of patients with polycythemia vera and to a lesser extent among patients with the other myeloproliferative disorders. We analyzed the effect of JAK2 on the expression of polycythemia rubra vera 1(PRV-1), using an in vitro model. Compared to wild-type JAK2, the presence of JAK2 increased both PRV-1 protein and mRNA levels in murine mye...
متن کاملPulmonary hypertension in patients with chronic myeloproliferative disorders.
Pulmonary hypertension (PH) is a severe haemodynamic disorder in which the pulmonary artery pressure is persistently elevated, leading to right-sided heart failure and death. Recently, chronic myeloproliferative diseases associated with pulmonary hypertension were included in the group 5 category, corresponding to PH for which the aetiology is unclear and/or multifactorial. In this review we wi...
متن کاملChronic myeloproliferative disorders.
The Philadelphia chromosome-negative chronic myeloproliferative disorders (CMPD), polycythemia vera (PV), essential thrombocythemia (ET) and chronic idiopathic myelofibrosis (IMF), have overlapping clinical features but exhibit different natural histories and different therapeutic requirements. Phenotypic mimicry amongst these disorders and between them and nonclonal hematopoietic disorders, la...
متن کاملLife expectancy of persons with chronic disabilities.
The life expectancy is an important summary measure of an individual's prognosis for survival. The life table is the preferred method for computing life expectancies, but it is not always feasible. We show that for several chronic disabilities, the logarithms of the age-specific mortality ratios (relative to the general population) decline linearly with age, reaching parity at age 85 or older. ...
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ژورنال
عنوان ژورنال: Cancer
سال: 1991
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19910515)67:10<2658::aid-cncr2820671042>3.0.co;2-c